Initial Dipeptide Formation in Hemoglobin Biosynthesis

Studies on Hemoglobin Biosynthesis: Asynchronous Synthesis of Hemoglobin a and Hemoglobin A2 by Erythrocyte Precursors.

The biosynthesis of human hemoglobin A1c. Slow glycosylation of hemoglobin in vivo.

Hemoglobin A1c, the most abundant minor hemoglobin component in human erythrocytes, is formed by the condensation of glucose with the N-terminal amino groups of the beta-chains of Hb A. The biosynthesis of this glycosylated hemoglobin was studied in vitro by incubating suspensions of reticulocytes and bone marrow cells with [3H]leucine or 59Fe-bound transferrin. In all experiments, the specific...

The utilization of glycine in the biosynthesis of hemoglobin.

Isotopic studies have demonstrated that glycine is used in the biosynthesis of hemoglobin. Glycine has been tagged in one of three ways: (a) with N’” in the amino group (l-3), (b) with Cl4 in the a-methylene carbon position (4), and (c) with Cl4 in the carboxyl group (5). When any of these three forms of glycine is fed to animals, the isotope is incorporated into hemoglobin, but interesting dif...

‏‎suppression of coke formation in thermal cracking by coke inhibitors‎‏

‏‎the main purpose of this research was to:1.develop a coking model for thermal cracking of naphtha.2.study coke inhibition methods using different coke inhibitors.developing a coking model in naphtha cracking reactors requires a suitable model of the thermal cracking reactor based on a reliable kinetic model.to obtain reliable results all these models shall be solved simultaneously.for this pu...

The dipeptide conformations of all twenty amino acid types in the context of biosynthesis

There have been many studies of dipeptide structure at a high level of accuracy using quantum chemical methods. Such calculations are resource-consuming (in terms of memory, CPU and other computational imperatives) which is the reason why most previous studies were restricted to the two simplest amino-acid residue types, glycine and alanine. We improve on this by extending the scope of residue ...